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| Name | Date of Office | |
|---|---|---|
| Philip R. Lee | Nov. 2, 1965 | Feb 16, 1969 |
| Roger O. Egeberg | July 14, 1969 | June 30, 1971 |
| Merlin K. DuVal | July 1, 1971 | Dec. 15, 1972 |
| Charles C. Edwards | Apr. 18, 1973 | Jan. 21, 1975 |
| Theodore Cooper | July 1, 1975 | Jan. 20, 1977 |
| Julius B. Richmond | July 13, 1977 | Jan. 20, 1981 |
| Edward N. Brandt, Jr. | May 14, 1981 | Dec. 1984 |
| James Mason (Actg) | Dec. 1984 | June 1986 |
| Robert E. Windom | June 23, 1986 | Mar. 5, 1989 |
| James O. Mason | Apr. 21, 1989 | |
| * Title of office was changed from assistant secretary for health and scientific affairs, November 1972. | ||
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