Institutes and Research Divisions
National Institute of Diabetes
and Digestive and Kidney Diseases*
Important Events in NIDDK History
NIDDK Legislative Chronology
Director's of NIDDK
Biographical Sketch of NIDDK Director
Special Programs Branch
P.L. 99-158 authorized the establishment of this program for the collection, storage, analysis, retrieval, and dissemination of data derived from patient populations with digestive diseases and, where possible, data involving general populations to detect individuals with a risk of developing digestive diseases.
Liver Transplantation Database Project. The purpose of the 7-year project is to establish a liver transplantation database with data gathered from patients and donors from several transplant centers in the United States. To answer questions about transplantation, data are being collected from patients who are undergoing liver transplantation for various acute and chronic liver diseases and malignancies. The data relate to patients' conditions prior to operation, and in early and late postoperative periods, and to donor livers and malignancies. The data will be evaluated and made available to investigators and clinicians.
Division of Kidney, Urologic and Hematologic Diseases
The division supports research on the physiology, pathophysiology, and diseases of the kidney, genitourinary tract, and the blood and blood-forming organs to improve or develop preventive, diagnostic, and treatment methods.
This program supports basic and clinical research studies of the normal and abnormal development, structure, and function of the genitourinary tract and the affect of diseases and disorders such as diabetes mellitus, spinal cord injury, and multiple sclerosis on these organs.
An area of emphasis is research that will increase the knowledge of the etiology, diagnosis, pathophysiology, therapy, and prevention of the major pediatric and adult urological diseases and disorders.
Also emphasized is basic research and clinical applications of diagnostic and therapeutic modalities such as 1) shock-wave and laser lithotripsy, 2) urolithiasis inhibitors, 3) bladder substitution procedures and devices, and 4) prostate growth inhibitor and reduction therapies.
Women's Health Program. This program encourages and supports basic and clinical research on urological problems that disproportionately affect women. Areas include urinary incontinence, urinary tract infections, and interstitial cystitis.
The HIV program supports basic and clinical studies on renal and genitourinary tract structure and function and hematopoietic function in individuals with HIV infection. Studies on HIV infection focus on the effect of HIV therapies on marrow function and clinical course of dialysis and transplant patients, potential interactions of HIV infection and the immunosuppressive therapy used to prevent transplant rejection and effect on organ function.
Centers Program. The George M. O'Brien Kidney and Urologic Research Centers conduct interdisciplinary investigations that address the basic, clinical, and applied aspects of biomedical research in renal and genitourinary physiology and pathophysiology, nephrology, and urology.
The goal of the centers is to reduce mortality and morbidity of kidney and urologic diseases by providing a focus and means for clinical and basic science disciplines to develop the knowledge needed to improve diagnosis, treatment, and prevention.
Clinical Trials Program. This program develops cooperative clinical trials to prevent major chronic kidney, genitourinary, and hematologic diseases.
Epidemiology Program.This program supports the development of epidemiologic data and research related to major kidney, genitourinary, and hematologic diseases. Coordinated under this program are the U.S. Renal Data System the kidney and urologic disease interview and examination component of the third National Health and Nutrition Examination Survey, 1988-94 and management of the epidemiology grants portfolio.
This program supports basic and clinical studies of normal and disease states of the hematopoietic system, including sickle cell anemia, thalassemia, aplastic anemia, iron deficiency anemia, thrombocytopenia, hemolytic anemia, and purpura. Areas of interest include morphologic, physiologic, and biochemical aspects of the formation, mobilization, and release of blood cells erythrocyte metabolism and physiology, globin synthesis, ion transport, and enzymatic pathways iron metabolism and absorption erythropoietin and other hematopoietic growth factors hemoglobin metabolism, structure, function, and genetic control porphyrins and prophyrias and metabolism and function of white blood cells and plasma serum proteins.
Office of the Director Advisory Boards