TH E   N I H    C A T A L Y S T     S E P T E M B E R  –  O C T O B E R   2008


The SIG Beat

News from and about the NIH Scientific Interest Groups

Mitochondria Mini-Symposium, November 19

The Mitochondria Interest Group is organizing an all-day mini-symposium on November 19, culminating with a WALS lecture by Leonard Guarente of MIT, titled "Sirtuins, Aging and Disease." The meeting will take place in Masur Auditorium, Building 10 on the NIH Bethesda campus. All are welcome to attend. Abstract deadline is October 15.

The mini-symposium is titled "The Interaction and Independence of Sirtuins and Mitochondria: A few NIH Perspectives." Sponsors include the National Institute on Aging, National Institute on Drug Abuse, the Office of Dietary Supplements, and the Office of Intramural Research.

Poster setup and registration begins at 7:45 a.m. Session I is 8:30 to 10:00 a.m. with three speakers: Karen Usdin (NIDDK), "The Dark Side of SIRT1"; John Hanover (NIDDK), "Sirtuins and O-GlcNAc: Interwoven threads in the fabric of the cellular stress response"; and Chuxia Deng (NIDDK) with a title to be announced.

Following a networking break and poster session, Session II begins at 10:30 a.m. with three speakers: Curtis Harris (NCI), title TBA; David Gius (NCI), "SIRT3 is a mitochondrial tumor suppressor gene"; and Barry Hoffer (NIDA), "Premature aging in POLG knock-in Mice".

Following lunch and poster session, Session III begins at 1:00 p.m. with three more speakers: Catherine Wolkow (NIA), "IIS and FOXO signaling in C. elegans: Unraveling the webs of direct and indirect targets that regulate longevity and diapauses"; Mark Mattson (NIA), "Adaptive stress response pathways in neurons"; and Toren Finkel (NHLBI), "Sirtuin regulation of mitochondrial function".

A networking break and poster session at 2:30 p.m. will lead to the WALS lecture by Guarente. Contact Steve Zullo of the NIH Center for Scientific Review at for more information.

New SIG: Retinal Disease Interest Group (RDIG)

The process of vision is initiated in the retina, which is the most accessible part of the central nervous system, supplying over 30 percent of the sensory input to the brain. Not surprisingly, visual (and specifically retinal) dysfunction is observed in numerous syndromic and inherited genetic diseases. The goal of RDIG is to promote interactions among scientists interested in biology, pathogenesis and treatments of syndromic diseases involving visual dysfunction or diseases of the neuronal tissues. Everyone is welcome to join and participate in lively discussions. The SIG leader is James Friedman (; 301-443-6758). Meeting times are generally the second Tuesday of the month (except in August).


Return to September-October 2008 Catalyst index

This page last updated on October 1, 2008, by Christopher Wanjek