FOR IMMEDIATE RELEASE
Thursday, January 2, 2003
Office of Communications
and Public Liaison
Stem Cell Research Boosted by Five New Grants at NIAMS
- Matricellular Proteins and Mesenchymal Stem Cells, Kurt D. Hankenson,
D.V.M., Ph.D., University of Michigan, Ann Arbor. This study investigates
the growth factors and hormones that influence how stem cells develop, which
should guide the development of therapies in bone diseases.
- Muscle Regeneration Through Stem Cell Transplantation, Johnny Huard, Ph.D., Children's Hospital of Pittsburgh, Pa., University of Pittsburgh Medical Center Health Systems. Stem cells are sometimes used in the body for regeneration. This study further examines the potential of stem cells from muscle for treating problems of musculoskeletal structure.
- Epidemiology of Connective Tissue Progenitor Populations, George F. Muschler, M.D., Cleveland Clinic Foundation, Cleveland, Ohio. This study examines how musculoskeletal stem cells contribute to the repair and remodeling of connective tissue.
- Stem Cell Therapy for Diseases of Bone in a Mouse Model, Christopher Niyibizi, Ph.D., University of Pittsburgh, Pa. This project uses a mouse model of osteogenesis imperfecta (brittle bone disease) to evaluate possibilities of regeneration or repair of bone marrow using mouse stem cells.
- Development of a GFP Sensitive Apoptosis Marker Gene, David W. Rowe, M.D., University of Connecticut School of Medicine, Farmington, Conn. This investigation will follow programmed cell activity-specifically, the life and death of a cell-and show how that activity generates a form of stem cells that are a factor in maintaining adult bone mass.
The mission of the National Institute of Arthritis and Musculoskeletal
and Skin Diseases (NIAMS), a part of the U.S. Department of Health and Human
Services' National Institutes of Health (NIH), is to support research into
the causes, treatment and prevention of arthritis and musculoskeletal and
skin diseases, the training of basic and clinical scientists to carry out
this research, and the dissemination of information on research progress in
these diseases. For more information about NIAMS, call the information clearinghouse
at (301) 495-4484 or (877) 22-NIAMS (free call) or visit the NIAMS Web site