NIH Consensus Development Conference to Assess Evidence on Celiac Disease|
The National Institutes of Health (NIH) will hold a Consensus Development
Conference on Celiac Disease, June 28-30, 2004 at the Natcher Conference
Center on the NIH campus in Bethesda, Maryland.
Celiac disease is a disorder primarily affecting the gastrointestinal
tract that is characterized by chronic inflammation of the mucosa,
which leads to atrophy of intestinal villi, malabsorption, and protean
clinical manifestations which may begin either in childhood or adult
life. Celiac disease's major genetic risk factors (HLA-DQ2 and HLA-DQ8),
and environmental trigger (specific peptides present in wheat, rye
and barley) have been identified and most patients experience complete
remission after exclusion of these grains from the diet. Thus, there
has been considerable scientific progress in understanding this
complex disease and in preventing or curing its manifestations by
dietary interventions. Still, a number of questions remain with
regard to the prevalence of celiac disease and appropriate testing
The upcoming conference will bring together epidemiologists, pediatricians,
gastroenterologists, pathologists, internists, and other specialists,
along with patients and their family members, to examine the evidence
available from various aspects of celiac disease research. Specifically,
the conference will address the following key questions:
- How is celiac disease diagnosed?
- How prevalent is celiac disease?
- What are the manifestations and long-term consequences of celiac
- Who should be tested for celiac disease?
- What is the management of celiac disease?
- What are the recommendations for future research on celiac disease
and related conditions?
During the first day and part of the second day of the conference,
experts will present the latest research findings in celiac disease
to the independent consensus panel. After weighing all of the scientific
evidence, the panel will prepare its statement addressing the questions
listed above. The panel will present its draft statement to the
public for comment at 9:00 a.m. on Wednesday, June 30. Following
this public comment session, and a subsequent executive session
to weigh the input provided, the panel will hold a news conference
at 2:00 p.m. to take questions from the media.
The primary sponsors of this conference are the National Institute
of Diabetes and Digestive and Kidney Diseases, and the Office of
Medical Applications of Research, NIH.
For additional information about this conference, please visit
the NIH Consensus Development Program Web site at http://consensus.nih.gov.
Note to TV Editors: The news conference at 2 p.m. on Wednesday,
June 30, 2004 will be broadcast live via satellite on the following
Galaxy 3 Transponder 07 C-Band
Orbital slot: 95 degrees West
Uplink Freq: 6065 Vertical
Downlink Freq: 3840 Horizontal
Test time: 1:30 - 2:00 p.m. ET
Broadcast: 2:00 - 3:00 p.m. ET
Note to Radio Editors: An audio report of the conference
results will be available after 4 p.m. June 30, 2004 from the NIH
Radio News Service by calling 1-800-MED-DIAL (1-800-633-3425).
NIH Videocasting will broadcast the conference live on the Internet.
Visit the Consensus Development Program homepage http://consensus.nih.gov/
or go directly to the NIH Videocast Web site http://videocast.nih.gov/
any day during the conference and look for the link to the
conference under "Today's Events."
The NIH comprises the Office of the Director and 27 Institutes
and Centers. The Office of the Director is the central office at
NIH, and is responsible for setting policy for NIH and for planning,
managing, and coordinating the programs and activities of all the
NIH components. The NIH is a component of the U.S. Department of
Health and Human Services.