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Rare gene glitch may hold clues for schizophrenia – 3

Narrator:  This is NIH Health Matters.  I’m Joe Balintfy. Scientists focusing on the gene called "viper two” have discovered a surprising link to schizophrenia.

Sebat: The VIPR2 gene helps to regulate learning and behavior. However, this gene was certainly not on anybody’s top ten list.

Narrator: Dr. Jonathan Sebat at the University of California San Diego explains that schizophrenia patients in a recent study were 14 times more likely to have multiple copies of the VIPR2 gene.

Sebat: There were duplications that occurred 14 times more frequently in patients than in controls.

Narrator:  For details on the study and how this rare genetic glitch may hold clues to screening and personalized treatments for schizophrenia, visit www.nimh.nih.gov.  Health Matters is produced by the National Institutes of Health, part of the U.S. Department of Health and Human Services.

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This page last reviewed on April 6, 2011

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