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Scientists Discover New Genetic Immune Disorder in Children – 1
Narrator: This is NIH Health Matters. A drug called Anakinra has proven effective against DIRA, a newly discovered auto inflammatory disease affecting newborns. Dr. Raphaela Goldbach-Mansky with the National Institute of Arthritis and Musculoskeletal and Skin Diseases says anakinra blocks the IL-1 pathway, which is a break in the immune system.
Dr. Goldbach-Mansky: It has to be given by daily injection, but there are other longer-acting IL-1 blocking agents that are being developed that might be effective, and I am in fact interested in testing one of such agents.
Narrator: Drug treatment and genetic testing for DIRA, caused by an IL-1 protein deficiency, is the best hope for newborns faced with the potentially fatal symptoms. For more details, visit www.nih.gov. Health Matters is produced by the National Institutes of Health, part of the US Department of Health and Human Services.
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