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Scientists get a close-up of opioid receptors - 1

Narrator: This is NIH health matters, I’m Joe Balintfy. Scientists are gaining insight into the structure of opioid receptors in the brain. Dr. Jean Chin at the NIH says opioid receptors are proteins that influence our moods and ability to experience pain.

Chin: The runner's high that you hear about. When people exercise they feel really good afterwards and that's because of the release of endorphins, and endorphins actually bind to these opioid receptors.

Narrator: Scientists have recently taken high-magnification pictures of several classes of opioid receptors. The pictures could help scientists understand how opiate-based drugs such as morphine and heroin interact differently with these receptors. For more information, visit www.nigms.nih.gov. Health Matters is produced by the National Institutes of Health, part of the U.S. Department of Health and Human Services.

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This page last reviewed on August 1, 2012

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