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Researchers Identify Gene Mutations Underlying Risk for Most Common Form of Parkinson's Disease – 2

Narrator: This is NIH Health Matters. Scientists pooled nearly 14,000 DNA samples to confirm that mutations in specific genes — present in the general population — are risk factors for Parkinson's disease. Dr. Andrew Singleton at the National Institute on Aging explains, scientists already identified five genes associated with Parkinson’s Disease.

Dr. Singleton: What we found with this latest study, is that two, and possibly three of those genes, also contained common variants that you or I have a very high chance of carrying.

Narrator: Dr. Singleton adds that these genetic mutations don’t cause Parkinson’s disease. Rather add to the risk by a small amount. For more information on this study, and Parkinson’s disease risk, visit www.nia.nih.gov. Health Matters is produced by the National Institutes of Health, part of the US Department of Health and Human Services.

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This page last reviewed on March 25, 2011

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