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Researchers Identify Gene Mutations Underlying Risk for Most Common Form of Parkinson's Disease – 3

Narrator: This is NIH Health Matters. A new study shows that two genetic mutations increase risk for Parkinson’s disease – these are called risk variants. However, added risk is small, only about 20-30 percent. Dr. Andrew Singleton at the National Institute on Aging explains that in one hundred people from the general population on average, about one would get Parkinson’s Disease.

Dr. Singleton: And if you were to take a hundred people from the general population, who all carried the risk variants that we found, about two people would, from that population, would get disease. So, it’s a fairly moderate increase in risk for disease.

Narrator: For more information on this study, and Parkinson’s disease risk, visit www.nia.nih.gov. Health Matters is produced by the National Institutes of Health, part of the US Department of Health and Human Services.

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This page last reviewed on March 25, 2011

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