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Mouse studies suggest treatment target for alcohol problems – 1
Narrator: This is NIH Health Matters. I’m Joe Balintfy. A recent study in mice shows a pathway in the brain’s reward circuitry appears to contribute to alcohol abuse.
Noronha: The study shows that excessive alcohol consumption leads to an activation of a signaling complex.
Narrator: Dr. Antonio Noronha [no-ROHN-ah] is with the National Institute on Alcohol Abuse and Alcoholism.
Noronha: This is a signaling complex of proteins called the mammalian target of rapamycin complex 1 or it's also abbreviated as mTORC1.
Narrator: mTORC1 has been linked to learning and memory. And because cellular problems underlying learning and memory can contribute to alcohol abuse disorders, researchers think that mTORC1 might be involved in alcohol problems. For details, visit www.niaaa.nih.gov. Health Matters is produced by the National Institutes of Health, part of the U.S. Department of Health and Human Services.
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