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Breast Cancer Stem Cells May Be Key to Multi-drug Resistance – 1

Narrator: This is NIH Health Matters. Multi-drug resistance occurs when, cancer cells in tumors for example no longer respond to multiple drugs. A study at the National Cancer Institute looks at how cancer stem cells might cause multi-drug resistance. Dr. Michael Gottesman, Director of Clinical Research at the National Cancer Institute says the study has examined hundreds of cancer cells and identified nearly four hundred causes of drug resistance.

Dr. Gottesman: Our general approach is to try to catalog all the ways in which cancer cells can become resistant to anti-cancer drugs.

Narrator: Dr. Gottesman says identifying common themes across cancer may lead to new therapies. For more information on multi-drug resistance and cancer research, visit www.cancer.gov. Health Matters is produced by the National Institutes of Health, part of the U.S. Department of Health and Human Services.

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This page last reviewed on March 14, 2011

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