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Breast Cancer Stem Cells May Be Key to Multi-drug Resistance – 4

Narrator: This is NIH Health Matters. As cancer progresses, it becomes more resistant to drugs. Dr. Michael Gottesman, director of Clinical Research at the National Cancer Institute explains, that’s why it’s important to diagnosis cancer early.

Dr. Gottesman: One of the problems with most patients who come to the doctor with a cancer is that the cancer is quite large, or has spread, and there are many, many cells. And the more cells you have the more likely that one or more will develop a resistance mechanism. So if you can get tumors when they are relatively small or not metastasized, then you are more likely, I think, to be successful with chemotherapy.

Narrator: For more on cancer treatments and research, visit www.cancer.gov. Health Matters is produced by the National Institutes of Health, part of the U.S. Department of Health and Human Services.

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This page last reviewed on March 14, 2011

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