NIH Radio
Skin Cancer Study May Pave Way for More Individualized Treatments – 2
Narrator: This is NIH Health Matters. At the National Human Genome Research Institute’s Cancer Genetics Branch, Dr. Yardena Samuels is studying skin cancer tumors.
Samuels: What we did was a genetic analysis of a group of enzymes called a matrix metalloproteinases or MMPs for short.
Narrator: MMPs have been implicated in tumor growth in a variety of cancer types.
Samuels: We systematically looked into these genes that encode these enzymes and we found out that about a quarter of human melanoma tumors have changes or mutations in genes that code for these enzymes and importantly we found a tumor suppressor gene.
Narrator: For details on melanoma, and more about medical research, visit www.nih.gov. Health Matters is produced by the National Institutes of Health, part of the US Department of Health and Human Services.
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