NIH Investigators Find Link Between DNA Damage and Immune Response – 3
Narrator: This is NIH Health Matters. I’m Joe Balintfy. Toll-like receptors are proteins that play a role in the immune system by defending the body from infection. Toll-like receptors interact with a tumor suppressor gene called p53 to regulate inflammation or swelling. Dr. Michael Resnick, a principal investigator at the National Institutes of Health explains, P53 helps prevent threats to the human body.
Resnick: It directs a set of genes to either tell cells to stop growing until they repair, tell some cells that have too much damage to die.
Narrator: He adds that p53 recognizes signals in chromosomes. For more information on the link between p53 and the immune system, visit www.niehs.nih.gov. Health Matters is produced by the National Institutes of Health, part of the U.S. Department of Health and Human Services.
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