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NIH Investigators Find Link Between DNA Damage and Immune Response – 4

Narrator:  This is NIH Health Matters.  I’m Joe Balintfy.  Researchers have established that the tumor suppressor gene called p53 which deals with chromosome or DNA damage, and determines whether cells are going to grow or survive after DNA damage, can also control the innate immune system, the body’s basic response to threats.

Resnick: And what we think is that may enhance the ability in some way to deal with infections or bacterial infections or viral infections.

Narrator: Dr. Michael Resnick, a principal investigator at the National Institutes of Health, says humans evolved an inflammatory response when subjected to DNA damage.  For more information on the link between DNA damage and the immune system, visit www.niehs.nih.gov.  Health Matters is produced by the National Institutes of Health, part of the U.S. Department of Health and Human Services.

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This page last reviewed on May 27, 2011

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