Blood Stem-Cell Transplant Regimen Reverses Sickle Cell Disease in Adults – 3
Narrator: This is NIH Health Matters. A new, simplified blood stem-cell transplant regimen, which does not use chemotherapy, has eliminated sickle cell disease in nine of 10 adults who were severely affected by the disease. Dr. John Tisdale at the NIH Molecular and Clinical Hematology Branch says both patient and donor bone marrow stem-cells were mixed.
Dr. Tisdale: So in 9 of the 10 patients that we transplanted, we have a mix of both the donor cells and the recipient cells and itís enough to completely switch the red blood cells over to the donor type.
Narrator: He adds that this regimen will likely have broad application to other diseases. For details on sickle cell disease and this discovery, visit www.niddk.nih.gov. Health Matters is produced by the National Institutes of Health, part of the U.S Department of Health and Human Services.
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