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Much Touted “Depression Risk Gene” May Not Add to Risk After All – 1

Narrator: This is NIH Health Matters. A certain gene long thought to increase a person’s risk for major depression actually may have no effect. National Institute of Mental Health senior investigator Dr. Kathleen Merikangas, says a recent study, published in the Journal of the American Medical Association, challenges a widely accepted approach to studying risk factors for depression.

Merikangas: When we put together the gene with stressful life events we did not find that people who had this particular gene were at increase risk for depression in the presence of life events.

Narrator: For more information, visit www.nimh.nih.gov. Health Matters is produced by the National Institutes of Health, part of the US Department of Health and Human Services.

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This page last reviewed on March 24, 2011

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