Gene Linked to Alzheimer's Disease Plays Key Role in Cell Survival – 4
Narrator: This is NIH Health Matters. I’m Joe Balintfy. A gene linked to Alzheimer's disease plays a key role in cell survival according to a new study.
Refolo: So it has very broad therapeutic implications.
Narrator: Dr. Lorenzo Refolo is at the National Institute on Aging.
Refolo: And will probably give more encouragement to the bio-pharmaceutical companies to pursue this drug target. But I think there's some more basic science that needs to be worked out.
Narrator: Dr. Refolo explains that the presenilin 1 gene enables brain cells to digest toxic proteins, but mutations in the gene disrupt this crucial function. For details on the study, which was lead by Dr. Ralph Nixon and funded in part by NIA, visit www.nia.nih.gov. Health Matters is produced by the National Institutes of Health, part of the U.S. Department of Health and Human Services.
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