NIH Radio
Preliminary Study Shows Creatine and Minocycline Warrant Further Study in Parkinson's Disease
Brief Description:
A National Institutes of Health sponsored clinical trial with 200 Parkinson's disease patients has shown that the over-the-counter supplement creatine and the antibiotic minocycline warrant further study in a large trial.
Transcript:
Schmalfeldt: A National Institutes of Health sponsored clinical trial with 200 Parkinson's disease patients has shown that the over-the-counter supplement creatine and the antibiotic minocycline warrant further study in a large trial. Dr. Diane D. Murphy, extramural program director for Parkinson's disease at the National Institute of Neurological Disorders and Stroke said these agents have interested medical investigators as they may have antioxidant properties.
Murphy: The studies we did so far were aimed at identifying drugs that would be worth pursuing in large scale clinical trials. So, in other words, the studies were aimed at eliminating those drugs that didn't meet the bar or shouldn't go into larger clinical trials. These drugs passed the bar and hopefully NINDS will be investing in larger trials soon.
Schmalfeldt: Study investigators caution that while the news is encouraging, the results don't demonstrate that these agents are effective in treating Parkinson's disease. Before these interventions can be recommended as a treatment, they must be tested in a larger trial with hundreds of patients. The study was published in the March 14 issue of Neurology. From the National Institutes of Health, I'm Bill Schmalfeldt in Bethesda, Maryland.
About This Audio Report
Date: 3/17/2006
Reporter: Bill Schmalfeldt
Sound Bite: Dr. Diane D. Murphy
Topic: Parkinson's Disease
Institute(s): NINDS
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