NIH Research Matters
September 29, 2014
A zebrafish study shed light on how the structure of the face forms. Problems with equivalent genes in people can cause facial defects and other developmental issues.
Researchers developed microgel particles that mimic platelets and help form blood clots. The approach could lead to new treatments for uncontrolled bleeding.
Scientists designed a way to target and destroy specific DNA sequences in microbes. The approach might one day be used against pathogenic bacteria resistant to multiple antibiotics.
September 22, 2014
Activating certain molecules in key tissues slowed aging in fruit flies. The findings could lead to a better understanding of aging processes in people.
By manipulating a protein called Stat3, researchers regenerated muscle in mice. The approach may point the way to treatments for muscle-wasting diseases.
Researchers described how a cell’s nucleus can act as a piston to propel it through a 3-D matrix. The findings may help in the design of strategies to regenerate tissue and inhibit metastatic cells.
September 15, 2014
Scientists used genomic sequencing technologies to identify the origin and track transmission of the Ebola virus in the current outbreak in Africa.
By analyzing the genomes of humans, flies, and worms, scientists are gaining insights into complex biological processes that are vital to human biology and disease.
Researchers identified a molecule that plays a role in heart failure in mice. The findings may lead to a new therapeutic agent to treat this common condition.
August 25, 2014
A combination drug treatment substantially reduced malaria in young children in Africa. The treatment could help reduce the disease burden among those most at risk.
A chikungunya vaccine gave encouraging results in an early-stage clinical trial. A vaccine could prevent outbreaks of the disease, which recently reached the U.S. mainland.
Scientists determined the detailed structural states of the glutamate receptor, which is involved in learning, memory, and several diseases.
August 18, 2014
Researchers found 108 genetic regions linked to schizophrenia, including 83 previously unrecognized. The findings suggest new avenues for potential treatments.
Scientists identified a gene that underlies a rare but devastating autoinflammatory condition in children. The study suggests a potential treatment for this and related diseases.
New tests rapidly and accurately diagnose Creutzfeldt-Jakob disease, an incurable and ultimately fatal neurodegenerative disorder. Such tests would have important clinical and research uses.
July 28, 2014
Depression is a common risk for people who’ve lost vision from age-related macular degeneration. A type of therapy called behavior activation can cut this depression risk in half.
Men exposed to cool temperatures for a month had an increase in brown fat along with changes in metabolism. The finding hints at new approaches to conditions such as obesity and diabetes.
Scientists used a novel microchip-based method to isolate and grow tumor cells circulating in blood. The technique provides an important step toward personalizing cancer therapy.
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About NIH Research Matters
Editor: Harrison Wein, Ph.D.
Assistant Editors: Vicki Contie, Carol Torgan, Ph.D.
NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.