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Lasker Clinical Research Scholars

Program Overview

The Lasker Scholars program aims to support successful candidates in two phases. Applicants will apply for an initial period of support in the Intramural Research Program. Selected scholars who successfully complete the initial phase will be able to remain within the IRP or to apply for extramural grant funding in the second phase. The first phase will support scholars in the IRP for 5 years, with the possibility of an extension of this phase for an additional 2 years. Lasker Scholars will be appointed as independent tenure-track investigators within an NIH Institute or Center, a process that includes being hired as a full time employee at the NIH and completing the procedures required of new Federal government employees. The IRP will provide space, research expenses, full salary, and Federal employee benefits. Scholars will develop independent research activities over the course of their stay in the IRP, and will be formally reviewed by a panel of senior extramural investigators every 2 to 4 years to evaluate their research progress.

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Upon successfully completing the initial IRP phase of the program, the Lasker Scholar will be eligible for two options in the second phase:

Option 1. Remain in the IRP with continued intramural funding and progression to tenured senior investigator status after appropriate assessment. Retention in the IRP will be dependent on the development of a mutual agreement between the Scholar and the IRP. Tenure at the NIH requires evaluation and approval by the NIH Deputy Director for Intramural Research.

Option 2. The Scholar can compete for an extramural research grant as an independent researcher, to be awarded by an extramural component of the NIH. This option will allow successful investigators to leave the IRP to continue their research at an extramural institution. Applicants who are completing the IRP phase will be eligible to submit a research grant application to NIH. Funding priority will be given to applicants who have demonstrated progress in their proposed research plans, and obtained an independent extramural position. The grant is expected to provide direct funding of up to $500,000/year (plus indirect costs) for up to 5 years/project periods at the extramural institution. If Scholars leave the Lasker program for an extramural position prior to 5 years of research in the IRP, they will not be eligible to apply for this funding priority, but they may be eligible for other kinds of extramural NIH research grants announced in the NIH Guide.

Research Areas of Interest

The Intramural Research Program will give highest priority to those applications which propose research within the fields given below, listed by participating Institutes/Centers.  In order to assure the programmatic appropriateness of the proposed research, applicants must obtain a Letter of Support, which will then be included with the full application.

National Cancer Institute

  • Medical oncology, pediatric hematology-oncology, radiation oncology, surgical oncology, pathology, neuro-oncology, urology and dermatology. Specific areas within these categories include genitourinary oncology, lymphoma/myeloma, neuron-oncology, immunotherapy, breast cancer, sarcoma, molecular diagnostics, and functional imaging.
  • Translational and clinical epidemiology, genetics of cancer

National Eye Institute

  • Neurodegenerative eye disease

National Heart, Lung, and Blood Institute

  • Cardiovascular blood and pulmonary research: regenerative medicine, pediatric and developmental biology
  • Cardiovascular research: heart failure, electrophysiology, interventional therapeutics
  • Blood research: chronic myeloproliferative disorders, benign hematology, bone marrow failure syndromes, myelodysplastic syndromes, hematological malignancies, and hematopoietic stem cell transplantation
  • Pulmonary research: pulmonary interstitial disease, pulmonary hypertension
  • Sickle cell research

National Human Genome Research Institute

  • Genomic medicine

National Institute on Alcohol Abuse and Alcoholism

  • Development of medications for treatment of diseases/disorders of addiction

National Institute of Allergy and Infectious Diseases

  • Hepatitis
  • Antimicrobial resistance (gram negative bacteria)
  • Food allergy

National Institute of Arthritis and Musculoskeletal and Skin Diseases

  • Rheumatology

Eunice Kennedy Shriver National Institute of Child Health and Human Development

  • Metabolic diseases
  • Bone growth and skeletal dysplasia
  • Endocrinology and molecular genetics
  • Regenerative medicine and stem cell biology
  • Reproductive and molecular medicine
  • Developmental biology and human genetics
  • Women’s health

National Institute on Dental and Craniofacial Research

  • Cilnically relevant models of bone regeneration, such as fracture healing or skeletal development
  • Clinically relevant models of modulators of bone regeneration such as aging, inflammation or skeletal disorders

National Institute of Diabetes and Digestive and Kidney Diseases

  • Gastroenterology
  • Nephrology
  • Endocrinology

National Institute of Environmental Health Sciences

  • Reproductive epidemiology
  • Environmental health science

National Institute on Drug Abuse

  • Development of medications for treatment of diseases/disorders of addiction

National Institute of Mental Health

  • Developmental neuropsychiatry/neuroscience with genetic or imaging interest

National Institute of Neurological Disorders and Stroke

  • Any area of neurology or stroke

National Institute of Nursing Research

  • Symptom science/biology within a clinical context
This page last reviewed on April 25, 2014

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