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Lasker Clinical Research Scholars

Program Overview

The Lasker Scholars program provides a unique opportunity for clinician-scientists to receive a combination of intramural and extramural NIH research support.. The program has two phases. The first phase will support scholars in the IRP for 5 years, with the possibility of an extension of this phase for an additional 2 years. Lasker Scholars will be appointed as independent tenure-track investigators within an NIH Institute or Center, a process that includes being hired as a full time employee at the NIH and completing the procedures required of new Federal government employees. The IRP will provide space, research expenses, full salary, and Federal employee benefits. Scholars will develop independent research activities over the course of their stay in the IRP, and will be formally reviewed by a panel of senior extramural investigators every 2 to 4 years to evaluate their research progress.

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Upon successfully completing the initial IRP phase of the program, the Lasker Scholar will be eligible for two options in the second phase:

Option 1. Remain in the IRP with continued intramural funding and progression to tenured senior investigator status after appropriate assessment. Retention in the IRP will be dependent on the development of a mutual agreement between the Scholar and the IRP. Tenure at the NIH requires evaluation and approval by the NIH Deputy Director for Intramural Research.

Option 2. The Scholar can receive up to 3 years of support to continue independent research at an extramural sponsoring institution. This support is contingent upon obtaining an appropriate extramural position at an eligible institution, and the successful NIH programmatic review of the scholar’s progress during the intramural phase of the award. Lasker Scholars can request direct costs of up to $499,000/year (plus applicable indirect costs). Scholars must complete 5 years of research in the IRP to be eligible for the extramural Lasker Scholars Grant.

Research Areas of Interest

The Intramural Research Program will give highest priority to those applications which propose research within the fields given below, listed by participating Institutes/Centers. Applicants are strongly advised to submit a Letter of Intent, to obtain feedback regarding the programmatic appropriateness of their research to the goals of the NIH intramural research program.

National Cancer Institute

  • Medical oncology, pediatric hematology-oncology, radiation oncology, surgical oncology, pathology, neuro-oncology, urology and dermatology. Specific areas within these categories include genitourinary oncology, lymphoid malignancies, neuro-oncology, immunotherapy, women's cancers, aeoro-digestive cancers, molecular diagnostics, and functional imaging.
  • Translational and clinical epidemiology, genetics of cancer

National Eye Institute

  • Neurodegenerative eye disease

National Heart, Lung, and Blood Institute

  • Cardiovascular blood and pulmonary research: regenerative medicine, pediatric and developmental biology
  • Cardiovascular research: heart failure, electrophysiology, interventional therapeutics
  • Blood research: chronic myeloproliferative disorders, benign hematology, bone marrow failure syndromes, myelodysplastic syndromes, hematological malignancies, and hematopoietic stem cell transplantation
  • Pulmonary research: pulmonary interstitial disease, pulmonary hypertension
  • Sickle cell research
  • Sleep disorders

National Human Genome Research Institute

  • Genomic medicine

National Institute of Allergy and Infectious Diseases

  • Hepatitis
  • Antimicrobial resistance
  • Allergy

National Institute of Arthritis and Musculoskeletal and Skin Diseases

  • Genetics, genomics, pathophysiology, prevention, and treatment of rheumatic diseases, particularly systemic lupus erythematosus, systemic vasculitis, inflammatory arthritis, inflammatory muscle disease, ankylosing spondylitis and spondyloarthropathies, and auto inflammatory syndromes. Psoriasis and inflammatory skin diseases.

Eunice Kennedy Shriver National Institute of Child Health and Human Development

  • Metabolic diseases
  • Bone growth and skeletal dysplasia
  • Endocrinology and molecular genetics
  • Regenerative medicine and stem cell biology
  • Reproductive and molecular medicine
  • Developmental biology and human genetics
  • Women’s health

National Institute of Diabetes and Digestive and Kidney Diseases

  • Gastroenterology
  • Nephrology
  • Endocrinology

National Institute of Environmental Health Sciences

  • Environmental health science

National Institute of Alcohol

  • Molecular genetics, optogenetic and neuroelectrical recording approaches in animals to probe circuit-level activity relevant to neuropsychiatric disorders

National Institute of Neurological Disorders and Stroke

  • Any area of neurology or stroke

National Institute of Nursing Research

  • Symptom science/biology within a clinical context
This page last reviewed on April 9, 2015

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