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Trans-NIH Mouse Initiatives Overweight Mice
Deltagen and Lexicon Knockout Mice and Phenotypic Data

List of Available Knockout Mice
The list below includes all knockout lines that have been obtained and are listed alphabetically by gene name.

To find out more about a particular gene, click on the gene symbol, which will take you to the Mouse Genome Informatics page that describes the gene and resources available for it.

To express interest in receiving the KO mouse materials when they become available ( see Fact Sheet ), click on the name of the repository distributing the line which will take you to the ordering page.

To see the phenotypic data on a mouse line, click on the "Data Sheet" link next to the gene you are interested in.

Gene Name
Gene Symbol
Repository Distributing Line
Phenotypic Data
ATP-binding cassette, sub-family A (ABC1), member 12
activin A receptor, type II-like 1
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
adenylate cyclase 3
adenylate cyclase 4
adenylate cyclase 7
adenylate cyclase 9
adipose differentiation related protein
adiponectin receptor 1
adiponectin receptor 2
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
aldehyde dehydrogenase family 7, member A1
apolipoprotein B editing complex 2
type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
ATPase, Na+/K+ transporting, alpha 1 polypeptide
arginine vasopressin receptor 1A
arginine vasopressin receptor 1B
AXL receptor tyrosine kinase
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
brain-specific angiogenesis inhibitor 2
bradykinin receptor, beta 1
baculoviral IAP repeat-containing 1a
bone morphogenetic protein 6
calcium channel, voltage-dependent, L type, alpha 1C subunit
calcium channel, voltage-dependent, alpha2/delta subunit 3
calcium channel, voltage-dependent, gamma subunit 3
calcium channel, voltage-dependent, gamma subunit 4
calcium channel, voltage-dependent, gamma subunit 6
calcitonin receptor
calpain 5
calpain 7
caspase 12
chemokine (C-C motif) receptor 6
chemokine (C-C motif) receptor 7
chemokine (C-C motif) receptor-like 1
chemokine (C-C motif) receptor-like 2
chemokine (C-C motif) receptor 1-like 1
CD97 antigen
cell division cycle 25 homolog A (S. cerevisiae)
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
cadherin EGF LAG seven-pass G-type receptor 2
cerberus 1 homolog (Xenopus laevis)
cofilin 1, non-muscle
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
carbohydrate (chondroitin 6/keratan) sulfotransferase 3
chloride channel calcium activated 5
cannabinoid receptor 2 (macrophage)
cathepsin C
chemokine (C-X-C motif) receptor 3
dopa decarboxylase
defensin beta 3
diacylglycerol O-acyltransferase 2
DNA methyltransferase 2
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
dopamine receptor 5
endothelial differentiation, G-protein-coupled receptor 6
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
estrogen related receptor, alpha
estrogen-related receptor gamma
exostoses (multiple) 1
fatty acid amide hydrolase
Fas apoptotic inhibitory molecule 2
FK506 binding protein 11
frizzled-related protein
frizzled homolog 1 (Drosophila)
frizzled homolog 6 (Drosophila)
frizzled homolog 8 (Drosophila)
frizzled homolog 9 (Drosophila)
frizzled homolog 10 (Drosophila)
gama-aminobutyric acid receptor associated protein
gamma-aminobutyric acid (GABA-B) receptor, 1
gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 3
gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 4
gamma-aminobutyric acid (GABA-A) receptor, pi
gamma-aminobutyric acid (GABA-A) receptor, subunit theta
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10
galanin receptor 1
galanin receptor 2
growth differentiation factor 6
glycine receptor, alpha 3 subunit
glycosyltransferase 8 domain containing 1
guanine nucleotide binding protein (G protein), gamma 7 subunit
glycoprotein m6a
G-protein coupled receptor 3
G protein-coupled receptor 6
G protein-coupled receptor 19
G protein-coupled receptor 37
G protein-coupled receptor 37-like 1
G protein-coupled receptor 82
G protein-coupled receptor 151
G protein-coupled receptor kinase 5
glutamate receptor, ionotropic, AMPA3 (alpha 3)
glutamate receptor, ionotropic, AMPA4 (alpha 4)
glutamate receptor, ionotropic, kainate 5 (gamma 2)
glutamate receptor ionotropic, NMDA3A
glutamate receptor, metabotropic 1
glutamate receptor, metabotropic 3
glutamate receptor, metabotropic 7
glycogen synthase kinase 3 beta
glutathione reductase 1
glutathione S-transferase, alpha 4
glutathione S-transferase, theta 2
hypocretin (orexin) receptor 1
heparan sulfate 6-O-sulfotransferase 2
5-hydroxytryptamine (serotonin) receptor 1D
5-hydroxytryptamine (serotonin) receptor 1F
5-hydroxytryptamine (serotonin) receptor 2B
5 hydroxytryptamine (serotonin) receptor 4
5-hydroxytryptamine (serotonin) receptor 5A
5-hydroxytryptamine (serotonin) receptor 5B
5-hydroxytryptamine (serotonin) receptor 6
5-hydroxytryptamine (serotonin) receptor 7
Insulin degrading enzyme
insulin-like growth factor binding protein 2
insulin-like growth factor 2, binding protein 1
inositol hexaphosphate kinase 1
interleukin 4 induced 1
interleukin 8 receptor, alpha
interleukin 21
interleukin 21 receptor
interleukin 23, alpha subunit p19
inositol polyphosphate-5-phosphatase A
insulin-like 5
IL2-inducible T-cell kinase
potassium voltage-gated channel, shaker-related, subfamily, member 6
potassium voltage-gated channel, subfamily H (eag-related), member 5
potassium large conductance calcium-activated channel, subfamily M, beta member 4
potassium voltage-gated channel, subfamily Q, member 2
K+ voltage-gated channel, subfamily S, 2
large tumor suppressor 2
LIM domain binding 2
lectin, galactose binding, soluble 8
Lipoic acid synthetase
limb region 1
limb region 1 like
low density lipoprotein receptor-related protein 5
Lutheran blood group (Auberger b antigen included)
MAP kinase-activated protein kinase 2
matrix metalloproteinase 10
matrix metalloproteinase 16
matrix metalloproteinase 17
myotubularin related protein 1
myotubularin related protein 2
myotubularin related protein 3
N-acetylglucosamine kinase
neural cell adhesion molecule 2
N-myc downstream regulated gene 3
neural precursor cell expressed, developmentally down-regulated gene 4
N-acetylneuraminate pyruvate lyase
nucleophosmin 1
neuregulin 1
neuregulin 4
neurotensin receptor 1
nucleobindin 2
oxidized low density lipoprotein (lectin-like) receptor 1
opioid receptor, delta 1
opioid receptor-like 1
opioid receptor, sigma 1
purinergic receptor P2X, ligand-gated ion channel, 7
phosphodiesterase 1B, Ca2+-calmodulin dependent
platelet-derived growth factor, C polypeptide
3-phosphoinositide dependent protein kinase-1
phosphatidylinositol 3-kinase, catalytic, beta polypeptide
phosphatidylinositol 3-kinase catalytic delta polypeptide
phosphatidylinositol-4-phosphate 5-kinase type1 beta
polycystic kidney disease 2-like 2
Pbx/knotted 1 homeobox
protein O-fucosyltransferase 2
protein-O-mannosyltransferase 1
peroxisome proliferator activator receptor delta
protein phosphatase 1F (PP2C domain containing)
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
protein phosphatase 1, catalytic subunit, beta isoform
protein phosphatase 5 catalytic subunit
PR domain containing 16
protein kinase C, nu
protease, serine, 12 neurotrypsin (motopsin)
presenilin enhancer 2 homolog (C. elegans)
patched homolog 2
prostaglandin E receptor 1 (subtype EP1)
protein tyrosine phosphatase, receptor type, O
pregnancy zone protein
RAB6B, member RAS oncogene family
regulator of G-protein signaling 2
regulator of G-protein signaling 4
regulator of G-protein signaling 5
regulator of G protein signaling 7
regulator of G-protein signalling 10
regulator of G-protein signaling 11
regulator of G-protein signaling 14
RIKEN cDNA 2210013K02 gene
RIKEN cDNA 4932417H02 gene
reticulon 4 receptor-like 1
reticulon 4 receptor-like 2
antimicrobial peptide RYA3
S100 calcium binding protein A1
soluble adenylyl cyclase
sodium channel, voltage-gated, type III, alpha
sodium channel, voltage-gated, type IX, alpha
sodium channel, voltage-gated, type XI, alpha
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
src homology 2 domain-containing transforming protein C1
sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)
SLAM family member 6
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
solute carrier family 6, member 11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
solute carrier family 9 (sodium/hydrogen exchanger), isoform 6
solute carrier family 12, member 6
solute carrier family 12 (potassium/chloride transporters), member 8
solute carrier family 17 (anion/sugar transporter), member 5
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
solute carrier family 22 (organic anion transporter), member 6
solute carrier family 22 (organic anion/cation transporter), member 12
solute carrier family 27 (fatty acid transporter), member 4
solute carrier family 35 (CMP-sialic acid transporter), member 1
solute carrier family 40 (iron-regulated transporter), member 1
solute carrier organic anion transporter family, member 1a5
steroid 5 alpha-reductase 2-like
somatostatin receptor 1
STIP1 homology and U-Box containing protein 1
syntaxin 4A (placental)
transforming growth factor, beta receptor I
thrombospondin 4
toll-like receptor 2
transmembrane protease, serine 11a
tripeptidyl peptidase I
transient receptor potential cation channel, subfamily C, member 2
transient receptor potential cation channel, subfamily M, member 5
twisted gastrulation homolog 1 (Drosophila)
thioredoxin domain containing 2 (spermatozoa)
ubiquitin carboxy-terminal hydrolase L1
Unc-51 like kinase 2 (C. elegans)
valosin containing protein
WAS protein family, member 2
chemokine (C motif) receptor 1