Other related projects:
The Mouse Transcriptome Project:
The Mouse Transcriptome Project is an NIH initiative that is generating
a free, public database of gene transcripts for many mouse tissues.
Currently, transcriptome data are available on more than 90 tissue
samples. These tissue-specific expression data, which are mapped
to the mouse genome, are available in a searchable format in the Mouse
Reference Transcriptome Database and at the Mouse
Reference Transcriptome .
The mouse was chosen for this effort because its genome has been
sequenced, because its tissues can be obtained under rigorous quality
control conditions, and because of its importance as a model for
the study of human biology and disease. For more information and
a description of transcriptomes, see http://www.genome.gov/13014330#6 .
The Mammalian Gene Collection
The Mammalian Gene Collection is a National Institutes of Health
(NIH) initiative that is building a collection of copies of human,
mouse and rat mRNA sequences in a form called complementary DNA (cDNA)
clones. The project, which is co-led by NHGRI and the National Cancer
Institute, is well over half of the way to its goal of providing
at least one cDNA clone for every known human and mouse gene.
Researchers can view the cDNA sequence data in a free, public database
located at the Mammalian Gene Collection .
They can also order copies of these cDNA clones and then insert them
into bacterial or mammalian cells, causing the cells to synthesize
the proteins encoded by that particular gene transcript. This enables
researchers to study the protein's properties in greater detail, as
well as to examine the effects that the protein and mutant versions
of the protein may have on various cell types.