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RFA on Developing the Potential of Xenopus Tropicalis as a Genetic Model The National Institutes of Health is soliciting applications to examine
the feasibility of using Xenopus tropicalis for standard genetic manipulations.
The research proposed should optimize the conditions required to perform
efficient, large-scale mutagenesis, and should use the optimized parameters
to perform small-scale mutagenesis; phenotyping; and gene cloning, identification,
and characterization. Mutant animals, protocols, and data produced by
these projects should be made available to the scientific community. We
anticipate that the mutants, data and procedures developed by the projects
funded under this Request for Applications (RFA) will enable Xenopus tropicalis
to play a significant role in identifying and characterizing genes that
regulate cellular and developmental processes. This RFA is co-sponsored
by the Trans-NIH Xenopus Working Group and by five Institutes (National
Institute of Child Health and Human Development, National Institute of
Neurological Diseases and Stroke, National Institute of General Medical
Sciences, National Institute of Environmental Health Sciences and National
Institute of Mental Health). This RFA will use the R01 grant mechanism. Collectively, the participating
institutes will provide up to $2.25 million (total cost) for the first
year of funding. |
