20190919-annexin.jpg

Cartoon of annexin A11 guiding hitchhiking through a neuron.

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Cartoon of annexin A11 guiding hitchhiking through a neuron.

Caption

Researchers discovered that annexin A11, a gene linked to a rare form of ALS, may play a critical role in the transport of RNA-encoded housekeeping instructions throughout neurons by hitching RNA granules onto traveling lysosomes and that disease-causing mutations prevent hitchhiking.

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Cartoon of annexin A11 guiding hitchhiking through a neuron.
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Cartoon of annexin A11 guiding hitchhiking through a neuron.