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November 20, 2011
Dr. Jane Salmon thanks the NIAMS for taking a risk in funding her team's PROMISSE study of lupus patients, despite what she calls its "unconventional" hypothesis. She describes the early NIAMS-funded mouse studies that led to PROMISSE's development and shares some of PROMISSE's results to date, including findings that suggest that women with lupus who have antiphospholipid antibodies are at increased risk for preeclampsia, a disease of pregnancy that endangers the lives of both fetuses and mothers. Salmon also notes data that show, importantly, that women with lupus who do not have antiphospholipid antibodies are likely to have a healthy pregnancy if their lupus is stable at conception.
This page last reviewed on April 22, 2015