March 19, 2013

Panel IV: Discussion of HPAI H5N1 GOF Research Case Studies

Day 1
4:30 -- 6:30 P.M. Panel IV: Discussion of HPAI H5N1 Gain-of-Function Research Case Studies

Presentations of Case Studies:

The panelists will be presented with and discuss case studies that illustrate how the HHS Framework, presented in Panel III, would apply to different HPAI H5N1 GOF research projects.

Discussion Questions:

  1. How well did the proposed Framework function in the analysis of the case studies? Is it a useful tool for guiding funding decisions?
  2. Does the Framework appropriately address the range of risks associated with the research?
  3. Does the Framework provide for the appropriate review of such research?
  4. Are there gaps that should be addressed by the Framework?

Panel Co-Moderators:

Dennis Dixon, Ph.D.
Chief, Bacteriology and Mycology Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, USA

Amy P. Patterson, M.D.
Associate Director for Science Policy, National Institutes of Health, USA


Tjandra Aditama, M.D.
Director-General, Disease Control and Environmental Health, Ministry of Health, Indonesia

Daniel Altmann, Ph.D. Head of Pathogens, Immunology and Population Health, Wellcome Trust, United Kingdom

Nancy Cox, Ph.D.
Director, Influenza Division, Office of Infectious Diseases, Centers for Disease Control and Prevention, USA

Thomas Inglesby, M.D.
Director, Center for Biosecurity, University of Pittsburgh Medical Center, USA

Joseph Kanabrocki, Ph.D.
Assistant Dean, Biosafety, and Associate Professor of Microbiology, University of Chicago, USA

Yoshihiro Kawaoka, D.V.M., Ph.D.
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, USA

J. S. Malik Peiris, M.D., Ph.D.
Professor, Centre of Influenza Research and the School of Public Health, The University of Hong Kong, China

Adel Mahmoud, M.D., Ph.D.
Professor, Molecular Biology and Public Policy, Princeton University, USA

Robin Robinson, Ph.D.
Director, Biomedical Advanced Research and Development Authority, Deputy Assistant Secretary for Preparedness and Response, Department of Health and Human Services, USA

This page last reviewed on April 20, 2015