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NIH Research Matters

June 29, 2015

Silhouette of a woman resting her head in her hands.

Study Shows Increase in Problem Drinking

A nationwide survey found that alcohol use disorder is becoming more common, but few people seek treatment. The study highlights the need for renewed education and treatment efforts.

Man cupping his hand to his ear.

Hearing Impairment in Hispanic/Latino Adults

Researchers found that nearly 1 in 7 Hispanic/Latino adults in the U.S. has hearing loss. More research will be needed to determine the factors involved and develop interventions.

Protein nanoparticle designed to fight HIV.

HIV Vaccine Progress in Animal Studies

Research teams achieved important steps needed to prompt the immune system to produce antibodies against HIV. The results show important progress toward design of an effective HIV vaccine.

June 15, 2015

Medical team meeting around female patient in hospital room.

Shorter Antibiotic Course Effective for Abdominal Sepsis

A 4-day course of antibiotics gave similar results to a longer standard course in people with complicated intra-abdominal infections. Shorter courses could have many benefits.

Fluorescein angiography image from a patient with proliferative diabetic retinopathy.

Protein Involved in Diabetic Eye Disease

Researchers identified a protein involved in advanced diabetic retinopathy. The finding may explain why reatments donít help all patients and suggests a new approach.

Lymphatic Vessels Discovered in Central Nervous System

Scientists found lymph vessels in mouse brains that carry fluid and immune cells from cerebrospinal fluid. Problems in this system might play a role in neurological disorders.

June 1, 2015

Scanning electron microscope image of cancer cell cluster within Cluster-Chip.

Microchip Captures Clusters of Circulating Tumor Cells

Researchers developed a device that captures rare clusters of tumor cells from the blood of cancer patients. The technique could lead to new insights into how cancer spreads.

Portion of a protein structure.

High-Resolution Imaging Technique May Advance Drug Design

Scientists resolved the detailed architecture of an inhibitor bound to an enzyme in solution. The technical advance could potentially aid drug development in the future.

Infant sucking motherís shoulder.

Mammary Gland May Have Epigenetic Memory

Results from a mouse study suggest that pregnancy primes the mammary gland for increased milk production in future pregnancies through epigenetic changes.

May 18, 2015

Photo of a retina.

Gene Therapy for Eye Disease Shows Benefits and Limitations

An experimental therapy for an inherited disorder that causes blindness improves vision, but the improvement declines with time. The findings offer insights for future therapies.

Illustration of person made of DNA.

Landscape of Gene Expression in the Human Body

A new resource allows scientists to examine how genomic differences affect gene activity in tissues and organs across the body—and how that activity influences susceptibility to diseases such as cancer, heart disease, and diabetes.

Neurons firing.

Controlling Brain Circuits in Mice

Researchers developed a tool that can turn specific sets of neurons on and off in mice to affect behavior. The technology can help scientists study mental health and disorders.

May 4, 2015

Ebola Virus.

Lipid Nanoparticle Therapeutic Treats Ebola in Monkeys

A newly designed agent was effective in treating monkeys infected with a deadly Ebola virus strain. The therapy is now being tested in Sierra Leone in people infected with Ebola.

Illustration of cylindrical device inside a tumor.

Devices Assess Cancer Drugs in Tumors

Two devices, developed independently, can gauge how tumors respond to various drugs. With further development, they could help determine ideal individual treatments.

Female doctor measuring blood pressure of senior woman

Structure of a Key Blood Pressure Regulator

Scientists revealed the molecular structure of a key target for blood pressure medications. The findings may aid the development of blood pressure drugs with fewer side effects.

April 27, 2015

Bag of transfusion blood.

Storing Blood Before Transfusion

Among patients undergoing complex cardiac surgeries, a clinical study found no advantage to only transfusing red blood cells stored for shorter periods of time.

Brain image.

Brain Mapping of Language Impairments

Researchers mapped different language impairments to specific brain regions to reveal the basic organization of our language system.

Artistís representation of oligodendrocyte.

Drugs Lessen Multiple Sclerosis Damage in Mice

In a mouse study, 2 drugs already on the market activated stem cells and repaired the type of brain damage seen in multiple sclerosis. The finding might lead to novel therapies.

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About NIH Research Matters

Editor: Harrison Wein, Ph.D.
Assistant Editors: Vicki Contie, Carol Torgan, Ph.D.

NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.

ISSN 2375-9593

Research News from NIH and Grantees

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This page last reviewed on June 29, 2015

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