PAR-25-154

HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)

R03

Preclinical

7/16/2026

PAR-25-051

Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

UG3/UH3

Preclinical

8/18/2026

RFA-AT-25-003

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

R15

Preclinical

11/23/2026

RFA-NS-25-023

HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)

R61/R33

Preclinical

1/15/2027

PA-24-185

Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)

K23

Workforce Development

5/7/2027

PA-24-194

NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)

K99/R00

Workforce Development

5/7/2027

PA-24-176

Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)

K01

Workforce Development

5/7/2027

PAR-25-100

Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)

R34

Implementation & Health Services, Recovery Services

5/8/2027

PAS-25-236

D-START: Data Science Track Award for Research Transition (D/START) (R03-Clinical Trial Optional)

R03

Data Dissemination & Secondary Analysis

9/7/2027

RFA-DA-26-055

Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)

R01

Data Dissemination & Secondary Analysis

12/3/2027

RFA-DA-26-056

Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)

R21

Data Dissemination & Secondary Analysis

12/3/2027

PA-25-302

NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

R03

Preclinical, Therapeutics Development, Prevention, Recovery Services, Implementation & Health Services, Life Course & Population, Data Dissemination & Secondary Analysis

1/7/2028

PA-25-304

NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)

R21

Preclinical, Therapeutics Development, Prevention, Recovery Services, Implementation & Health Services, Life Course & Population, Data Dissemination & Secondary Analysis

1/7/2028

PA-25-301

NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

R01

Preclinical, Therapeutics Development, Prevention, Recovery Services, Implementation & Health Services, Life Course & Population, Data Dissemination & Secondary Analysis

1/7/2028

PAR-25-446

Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

UG3/UH3

Therapeutics Development

8/21/2028

PA-26-001

Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

UG3/UH3

Preclinical, Therapeutics Development, Prevention, Recovery Services, Implementation & Health Services, Life Course & Population, Data Dissemination & Secondary Analysis

11/30/2028

FOR-NS-25-002

Forecast for HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional),

UG3/UH3

Therapeutics Development

FORECASTED

RFA-NS-25-031

HEAL Initiative: Pain Management Effectiveness Research Network: Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

UG3/UH3

Therapeutics Development, Implementation & Health Services

FORECASTED

RFA-TR-26-002

Limited Competition: HEAL Initiative Resource Centers for the Pain Management Effectiveness Network (ERN) (Clinical Trial Not Allowed)

ERN

Therapeutics Development, Implementation & Health Services

FORECASTED

FOR-DA-26-001

HEAL: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)

R61/R33

Prevention, Recovery Services, Implementation & Health Services

FORECASTED

FOR-DA-27-001

HEAL Initiative: Integrative Management of Chronic Pain and Opioid Use Disorder (OUD) for Whole Recovery: Health Systems

IMPOWR

Implementation & Health Services

FORECASTED

RFA-DA-27-006

HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center

IMPOWR/BEACON

Implementation & Health Services

FORECASTED

FOR-DA-26-002

Limited Competition for the HEAL Initiative: HEALthy Brain and Child Development (HBCD) Study (Collaborative U01- Clinical Trial Not Allowed)

U01

Life Course & Population

FORECASTED

FOR-DA-26-003

Limited Competition for the HEAL Initiative: HEALthy Brain and Child Development (HBCD) Study – Coordinating Administrative Core and Data Coordinating Center (U24 Clinical Trial Not Allowed)

U24

Life Course & Population

FORECASTED