In the News

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NIH launches study to test combination antibody treatment for HIV infection

September 20, 2018 — Clinical trial will evaluate whether treatment is safe for people living with HIV.

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NIH begins clinical trial of live, attenuated Zika vaccine

August 16, 2018 — Vaccinations have begun in a first-in-human trial of an experimental live, attenuated Zika virus vaccine developed by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

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NIH and VA collaborate to boost veterans’ access to cancer clinical trials

July 10, 2018 — Veterans with cancer who receive treatment from the Department of Veterans Affairs (VA) will now have easier access to clinical trials of novel cancer treatments, thanks to an agreement between VA and the National Cancer Institute (NCI), part of the National Institutes of Health.

CT scans from cancer patient

New approach to immunotherapy leads to complete response in breast cancer patient unresponsive to other treatments

June 4, 2018 — A novel approach to immunotherapy developed by researchers at the National Cancer Institute (NCI) has led to the complete regression of breast cancer in a patient who was unresponsive to all other treatments.

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NCI-MATCH precision medicine clinical trial releases new findings, strengthens path forward for targeted cancer therapies

June 4, 2018 — Results could play a role in bringing targeted treatments to patients with certain gene abnormalities, regardless of their cancer type.

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NIH begins large HIV treatment study in pregnant women

January 24, 2018 — Clinical trial will compare three antiretroviral drug regimens.

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Unique Trial Aims to Decrease Early Deaths in Patients with Rare Leukemia

January 3, 2018 — It’s not often that a cancer clinical trial recruits a handful of oncologists to staff a round-the-clock help desk of sorts for their peers. But that’s the case for a unique NCI-funded trial that is attempting to address a serious problem for patients who have a very rare cancer, acute promyelocytic leukemia (APL).

Peanut, eggs and milk.

Omalizumab improves efficacy of oral immunotherapy for multiple food allergies

December 11, 2017 — Combination allows more than 80 percent of children to safely consume at least two foods to which they were allergic.

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NIAAA Scientists Provide More Evidence that Binge Drinking May Be an Indicator for Vulnerability to Alcohol Use Disorder

November 28, 2017 — A recent NIAAA study has shown that people who drink socially and have certain risk factors for alcohol use disorder (AUD) self-administer more alcohol and at a faster rate during a single session of alcohol consumption in a laboratory setting than people at low risk for developing AUD.

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Data from landmark NIH blood pressure study supports important part of new AHA/ACC hypertension guidelines

November 13, 2017 — The new high blood pressure guidelines illustrate the utility and impact of NHLBI scientific studies.

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Progress on two Ebola vaccines

October 17, 2017 — Two test vaccines for Ebola were safe and induced lasting immune responses in a study with 1,500 adults in Liberia. The findings are an important step in development of a vaccine.

A radiology technician reviews a mammogram.

NCI-funded TMIST study compares 2-D and 3-D mammography for finding breast cancers

September 26, 2017 — The TMIST study is enrolling 165,000 women to compare 2-D and 3-D mammography for finding breast cancers. This NCI and ECOG-ACRIN press release describes the trial.

Jennifer Nsenkyire

For diversity in clinical trials, “Include us!”, patients say

September 19, 2017 — They ranged in age from 15 to 61—four African American women, all with stories to tell about their struggles with sickle cell disease, all with stories about a common experience that helped them through those struggles: participating in clinical trials.

John T. Schiller and Douglas R. Lowy standing in front of the NCI logo

NCI’s Douglas R. Lowy and John T. Schiller to receive 2017 Lasker Award

September 6, 2017 — Two scientists at the National Cancer Institute (NCI) will receive the 2017 Lasker-DeBakey Clinical Medical Research Award for their significant research leading to the development of human papillomavirus (HPV) vaccines.

Girl swimming in a double helix.

A girl’s limbs were oddly floppy. A lucky encounter helped explain why.

August 7, 2017 — Elena Silva and Brian Woodward sought a diagnosis for their daughter, Gabriela, who had an unknown muscle disorder that left her limbs to appear “floppy.” Silva had a chance encounter at the Cure CMD networking event for researcher and families affected by rare neuromuscular disorders at the NIH’s Clinical Center that led to Gabriela’s diagnosis.

NCI-Children's Oncology Group Pediatric MATCH Trial

NCI-COG Pediatric MATCH trial to test targeted drugs in childhood cancers

July 24, 2017 — An NCI-COG press release about the launch of a nationwide clinical trial that aims to match targeted treatments to pediatric cancers with specific genetic mutations.

NF1 protein structure.

Early-phase trial demonstrates shrinkage in pediatric neural tumors

December 28, 2016 — The drug selumetinib shrunk neural tumors in children with plexiform neurofibromas.

HHS Final Rule and NIH Policy on Clinical Trials Reporting – Dr. Francis Collins, NIH

HHS takes steps to provide more information about clinical trials to the public

September 16, 2016 — The new rule expands the legal requirements for submitting registration and results information for clinical trials involving U.S. Food and Drug Administration (FDA)-regulated drug, biological and device products.

Mother standing with daughters.

NCI launches largest-ever study of breast cancer genetics in black women

July 6, 2016 — The Breast Cancer Genetic Study in African-Ancestry Populations initiative is a collaborative research project that will identify genetic factors that may underlie breast cancer disparities. It is the largest study ever to investigate how genetic and biological factors contribute to breast cancer risk among black women.

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Landmark NIH study shows intensive blood pressure management may save lives

September 11, 2015 — Lower blood pressure target greatly reduces cardiovascular complications and deaths in older adults.

Metastatic melanoma cells.

NIH-Backed Study Provides Insight into Genetic Drivers of Melanoma

June 18, 2015 — A comprehensive analysis of the genomes of melanoma, a potentially deadly form of skin cancer, has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive the development of this disease.


NCI-MATCH trial will link targeted cancer drugs to gene abnormalities

June 1, 2015 — Study to examine targeted therapies for tumors with specific gene mutations regardless of cancer type.

The retina, the light-sensitive tissue at the back of the eye.

NIH-funded study points way forward for retinal disease gene therapy

May 4, 2015 — Benefits for Leber congenital amaurosis peak after one to three years, then diminish.

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Study finds peanut consumption in infancy prevents peanut allergy

February 23, 2015 — An NIH-funded clinical trial compares consumption and avoidance of peanut.

Illustration showing the retina as seen through a dilated pupil.

Eylea outperforms other drugs for diabetic macular edema with moderate or worse vision loss

February 19, 2015 — Lucentis and Avastin perform similarly to Eylea when vision loss is mild, NIH study shows.

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Stem Cell Transplants May Halt Progression of Multiple Sclerosis

December 29, 2014 — An NIH-funded clinical trial yields encouraging early results in some people with relapsing-remitting multiple sclerosis, the most common form of MS.

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NIH Begins Early Human Clinical Trial of VSV Ebola Vaccine

October 22, 2014 — Human testing of a second investigational Ebola vaccine candidate is under way at the National Institutes of Health’s Clinical Center in Bethesda, Maryland.

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Research Updates — The Environment and Breast Cancer

October 21, 2014 — In honor of Breast Cancer Awareness month in October, NIEHS is highlighting several breast cancer research advances that occurred this year as a result of the Sister Study.

Dr. Jeffrey Abrams

A Clinical Trial System for the Era of Precision Cancer Medicine

August 7, 2014 — Precision medicine recognizes that each person’s cancer is unique, and that, as much as possible, treatment must be selected based upon the alterations seen in each tumor.

A premature baby.

Telemedicine catches blinding disease in premature babies

June 26, 2014 — Telemedicine is an effective strategy to screen for the potentially blinding disease known as retinopathy of prematurity (ROP), according to a study funded by the National Eye Institute (NEI).

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Study finds stronger nicotine dependency associated with higher risk of lung cancer

June 19, 2014 — People who are highly addicted to nicotine — those who smoke their first cigarette within five minutes after awakening — are at higher risk of developing lung cancer than those who wait for an hour or more to smoke.

Black and white scan of lung with arrows pointing to metastatic tumors that have shrunk.

NIH study demonstrates that a new cancer immunotherapy method could be effective against a wide range of cancer

May 8, 2014 — A new method for using immunotherapy to specifically attack tumor cells that have mutations unique to a patient’s cancer has been developed by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health.

The optic nerve swelling.

Glaucoma drug helps women with blinding disorder linked to obesity

April 22, 2014 — An inexpensive glaucoma drug, when added to a weight loss plan, can improve vision for women with a disorder called idiopathic intracranial hypertension (IIH), according to a study funded by the National Institutes of Health.

A child wearing a contact lens. A green dye is used to evaluate the fit of hard lenses.

Contacts better than permanent lenses for babies after cataract surgery

March 6, 2014 — For adults and children who undergo cataract surgery, implantation of an artificial lens is the standard of care. But a clinical trial suggests that for most infants, surgery followed by the use of contact lenses for several years — and an eventual lens implant — may be the better solution.

This page last reviewed on November 7, 2018