Research
All of Us Research Program
Research
The All of Us Research Program is building a dataset to help transform the future of health research by equipping researchers with expansive health data shared by a diverse participant cohort. The All of Us dataset is disease agnostic and can support research on various aspects of health. Thousands of health researchers are already leveraging this one-of-a-kind dataset to improve understanding of health and disease, identify opportunities to reduce disparities, and enable more precise approaches to care.
About the Research Hub
The All of Us Research Hub stores health data from a diverse group of participants from across the United States. Visit the Research Hub to:
- Use the interactive Data Browser. The Data Browser provides interactive views of the publicly available All of Us Research Program participant data. Currently, participant-provided information, including data from surveys, wearable devices, physical measurements taken at the time of participant enrollment, and electronic health records (EHRs), is available.
- View Data Snapshots. These aggregated, public-facing data snapshots provide an overview of All of Us Research Program participant characteristics and the types of data that the program collects from participants.
- Read about All of Us data sources and methods of data curation.
- Find information about privacy and security processes that help keep participant data safe.
Get the Latest Researcher Updates
Subscribe to the quarterly All of Us Research Roundup newsletter to stay connected with all things All of Us research. You'll receive the latest All of Us news, funding opportunities, and more!
Researcher Workbench
The Research Hub also houses the Researcher Workbench platform and its suite of custom tools. The Workbench offers access to additional levels of data, workspaces, a cohort builder, and an interactive notebook environment. These tools are available to registered All of Us researchers.
Only researchers whose institutions have signed a Data Use and Registration Agreement (DURA) may register for the Researcher Workbench. An institutional signing official must sign this agreement. You can check your institution's access on the Research Hub. Register for access.
Benefits for Researchers
The All of Us Research Program's centralized, secure, cloud-based platform enables researchers across a wide range of settings and institutions and at all stages of their careers (e.g., students, early-stage investigators), to conduct rapid, hypothesis-driven research with just a computer and an Internet connection.
Researcher Access to Genomic Data
Within the Researcher Workbench's Controlled Tier, genomic data are integrated alongside data from surveys, physical measurements, EHRs, and wearables. The data and tools are available only to registered researchers who have taken additional steps and training to access these data. Using these datasets, researchers have opportunities to:
- Make associations through an integrated dataset by cross-referencing biologic data with data related to participants' environment and life circumstances
- Build upon the traditional longitudinal study model by layering dense, omic data from a large, diverse population
- Come together with other researchers from different disciplines around project-specific data analysis (through collaborative workspaces, cohort-building tools, interactive notebooks, etc.)
- Learn from sample cohorts for replicability and to help get started
- Leverage innovations of other studies and cohorts
Guidelines for Applicants to Funding Opportunities
To help promote equal opportunity for researchers to use All of Us resources, a core value of the program, we've assembled guidance for prospective applicants.
Data Resources
Participants share data from multiple sources. The All of Us Research Program's Data and Research Center curates and validates these data as part of the data collection process. An NIH Letter of Support from All of Us is NOT necessary if a researcher is seeking funding to use the data available on the Researcher Workbench.
All of Us Resources Beyond Data
Access to Biosamples and Contact with Participants for Partnered Research Studies
Access to biosamples and contact with participants for partnered research studies, or ancillary studies, is currently available only to researchers affiliated with NIH Institutes, Centers, and Offices whose proposals have been approved by the program. Researchers outside of NIH will be eligible to submit proposals in the future. At that time, All of Us will share guidance on how to apply and request a letter of support for funding applications. For more information, visit our Partnered Research Studies page.
Questions? Contact [email protected].
Access to All of Us Operations
Studying the All of Us Research Program's structure and/or programmatic activities is not currently supported. The program will announce approximate timeframes for considering access requests so researchers can prepare in advance. Announcements will include information on the procedures, policies, and requirements for access.
Funding Opportunities
Questions? Contact us.
Research Projects Directory
Researchers use All of Us data to study many different things about health. The program's tiered data access allows registered researchers to work with different data types, such as electronic health record data and genomic data, while also protecting participant privacy.
Researchers provide these project descriptions on the Research Hub. Any views expressed belong to those researchers and do not represent the views of the All of Us Research Program. If you have any concerns about a project, open the project description and request a formal review.
All of Us offers tiered access to data
- Registered Tier: Gives researchers access to data from electronic health records, survey answers, physical measurements, and wearables like Fitbit devices. Registered Tier data is adjusted to lower the chance that a researcher could identify any one participant. For example, researchers cannot see a participant's exact location, only the state where they live.
- Controlled Tier: Gives researchers access to the same data types available in the Registered Tier, as well as genomic data. This tier also includes more specific demographic data. For example, researchers can see the first three digits of participants' ZIP codes. Neither tier includes direct identifiers, such as participants' names or addresses.
Scientific publication summaries
Read our Research Highlights for a snapshot of how our researchers use All of Us data and tools to better understand health and disease.
Browse publications made possible by All of Us data and tools.
Safeguards to protect participant privacy
Our rigorous security models, access requirements, and data use policies help ensure that data is protected and used ethically and responsibly. To access the Researcher Workbench's Registered and Controlled Tiers, researchers must register with the program, verify their identity, take our Responsible Conduct of Research training, and agree to a code of conduct for responsible data use. They must also share what their project is and how they plan to use the data. For more information, visit our Privacy Safeguards page.
This page last reviewed on
