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Succinate dehydrogenase and its component part
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The enzyme succinate dehydrogenase processes oxygen to supply energy to the cell. It is embedded in the outer membrane of mitochondria, cellular structures which supply energy to the cell. The enzyme is made up of parts, or subunits. The researchers found that some patients with GIST had mutations in the genes for the B and C subunits of the enzyme. In other cases, the enzyme failed to function.
Description
The enzyme succinate dehydrogenase processes oxygen to supply energy to the cell. It is embedded in the outer membrane of mitochondria, cellular structures which supply energy to the cell. The enzyme is made up of parts, or subunits. The researchers found that some patients with GIST had mutations in the genes for the B and C subunits of the enzyme. In other cases, the enzyme failed to function, presumably because of other, as yet undiscovered, mutations.
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Succinate dehydrogenase and its component part