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20210728-als.jpg
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Title
CHMP7 mislocalization damages the nuclear pore of ALS neurons
Caption
When CHMP7 accumulates in the nucleus, certain proteins become missing from nuclear pores (outlined in white). This causes the pores to break apart, leading to downstream effects that may cause ALS.
Credit
Rothstein Lab
Description
When CHMP7 accumulates in the nucleus, certain proteins become missing from nuclear pores (outlined in white). This causes the pores to break apart, leading to downstream effects that may cause ALS.
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Alt Text
When CHMP7 accumulates in the nucleus, certain proteins become missing from nuclear pores (outlined in white). This causes the pores to break apart, leading to downstream effects that may cause ALS.