A high-fat diet caused mitochondria (purple) in white fat cells to become fragmented and less effective at burning energy (left panel). In mice that lacked RalA, the absence of RalA prevented this fragmentation (right panel) and preserved the energy production of mitochondria. The large lipid (fat) droplets in fat cells appear green.
Credit
UC San Diego Health Sciences
Description
Mitochondria surrounding lipid droplets appear brighter in right panel.