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The central amygdala (CeA) functions as a pain rheostat in the forebrain, enhancing or attenuating pain. Modulation of pain is accomplished by cell-type-specific changes in activity after injury. Activity in CeA-PKCδ neurons drives increases in pain-relat
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The central amygdala (CeA) functions as a pain rheostat in the forebrain, enhancing or attenuating pain. Modulation of pain is accomplished by cell-type-specific changes in activity after injury. Activity in CeA-PKCδ neurons drives increases in pain-related behaviors whereas activity in CeA-Som neurons reduces pain-like behaviors.
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The central amygdala (CeA) functions as a pain rheostat in the forebrain, enhancing or attenuating pain. Modulation of pain is accomplished by cell-type-specific changes in activity after injury. Activity in CeA-PKCδ neurons drives increases in pain-relat