Menopausal Hormone Therapy Information

New findings from the Women’s Health Initiative and other studies offer important information about the risks and benefits of long-term menopausal hormone therapy. The links below point to information resources, including the most current from the NIH, on both long-term and short-term hormone use, and other concerns related to women's health during and after menopause.

Women’s Health Initiative Hormone Therapy Study

• WHI Study Data Confirm Short-Term Heart Disease Risks of Combination Hormone Therapy for Postmenopausal Women, February 15, 2010 — National Heart, Lung, and Blood Institute (NHLBI)
• Analyses from the WHI: Effect of Hormone Therapy on Risk of Heart Disease May Vary by Age and Years Since Menopause, April 3, 2007 — National Heart, Lung, and Blood Institute (NHLBI)
• Women's Health Initiative — National Heart, Lung, and Blood Institute (NHLBI)
• Findings from the Estrogen-Alone Study — National Heart, Lung, and Blood Institute (NHLBI)
• Findings from the Estrogen Plus Progestin Study — National Heart, Lung, and Blood Institute (NHLBI)

Menopausal Hormone Therapy

• Menopause and Hormones: Common Questions — Food and Drug Administration
• Menopausal Symptoms: Comparative Effectiveness Review of Therapies — Agency for Healthcare Research and Quality
• Hormones and Menopause — National Institute on Aging (NIA)
• Estrogen and Estrogen with Progestin Therapies for Postmenopausal Women — Food and Drug Administration
• Menopausal Hormone Replacement Therapy — National Cancer Institute (NCI)
• National and regional health resources on Hormone Replacement Therapy — MedlinePlus
• Hormone Replacement Therapy for the Prevention of Chronic Conditions in Postmenopausal Women — U.S. Preventive Services Task Force
• Decrease in Breast Cancer Rates Related to Reduction in Use of Hormone Replacement Therapy, April 18, 2007 — National Cancer Institute (NCI)

Menopause

• Age Page: Menopause — National Institute on Aging (NIA)
• Menopause: Time For a Change — National Institute on Aging (NIA)
• NIH State-of-the-Science Conference on Management of Menopause-Related Symptoms, March 21-23, 2005 — National Institute on Aging (NIA) and the Office of Medical Applications of Research (OMAR)
• Black Cohosh — National Center for Complementary and Alternative Medicine and Office of Dietary Supplements
• Menopausal Symptoms and CAM — National Center for Complementary and Alternative Medicine (NCAMM)

Osteoporosis

• Osteoporosis — NIH Osteoporosis and Related Bone Diseases — National Resource Center (supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) with contributions from the National Institute on Aging (NIA), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute of Dental and Craniofacial Research (NIDCR), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH Office of Research on Women’s Health (NIH-ORWH), and HHS Office on Women’s Health)
• Osteoporosis — National Institute on Aging (NIA)

Dementia

• Rates of Dementia Increase Among Older Women on Combination Hormone Therapy — National Institute on Aging (NIA)
• Estrogen Plus Progestin and the Incidence of Dementia and Mild Cognitive Impairment in Postmenopausal Women — Journal of the American Medical Association
• Effect of Estrogen Plus Progestin on Global Cognitive Function in Postmenopausal Women — Journal of the American Medical Association
• Alzheimer's Disease Education and Referral (ADEAR) Center — National Institute on Aging (NIA)

Understanding Risk

• Understanding Risk: What Do Those Headlines Really Mean? — National Institute on Aging (NIA)