September 20, 2016

Children’s Health and Exposure Analysis Resource Core/Human Health Exposure Analysis Resource Core

The ECHO Children’s Health and Exposure Analysis Resource (CHEAR) Core serves as a consortium resource for laboratory and statistical analyses of personal environmental exposures in existing and future collections of biological samples. It builds on a foundation of the existing CHEAR resource, which was established to provide a focused infrastructure for comprehensive exposure analysis of biological samples to provide 1) rigorous assessment of a range of environmental exposures, xenobiotics, physiological measurements, and other biological indicators of environmental exposure and response and 2) statistical tools and data science approaches to manage and analyze newly generated datasets in a cohesive and integrated manner.  The resources developed under CHEAR are an integral component of the ECHO program in providing state-of-the-art analytical support to measure environmental exposures for the extant cohorts solicited under ECHO.


  • Icahn School of Medicine at Mount Sinai, New York City, New York
  • RTI, Research Triangle Park, North Carolina
  • University of Minnesota, Minneapolis, Minnesota
  • Wadsworth Center, Albany, New York
  • Westat, Inc., Rockville, Maryland

Human Health Exposure Analysis Resource Core

In 2019, NIH will build upon the success of CHEAR by offering exposure analysis resources to researchers studying health outcomes that occur later in life. The expanded program, called the Human Health Exposure Analysis Resource (HHEAR), will provide a larger community of researchers access to centralized, high-quality exposure assessment services. This will allow researchers to better understand the influence of environment on health throughout the life-course and eventually support more comprehensive assessment of the developmental origins of health and disease.

This page last reviewed on November 14, 2019