Human Health Exposure Analysis Resource Core

The ECHO Human Health and Exposure Analysis Resource (HHEAR) Core serves as a consortium resource for laboratory and statistical analyses of personal environmental exposures in existing and future collections of biological samples. HHEAR, previously known as Children’s Health and Exposure Analysis Resource Core (CHEAR) resource, was established to provide a focused infrastructure for comprehensive exposure analysis of biological samples to provide 1) rigorous assessment of a range of environmental exposures, xenobiotics, physiological measurements, and other biological indicators of environmental exposure and response and 2) statistical tools and data science approaches to manage and analyze newly generated datasets in a cohesive and integrated manner. The resources developed under HHEAR are an integral component of the ECHO program in providing state-of-the-art analytical support to measure environmental exposures for the extant cohorts solicited under ECHO. This will allow researchers to better understand the influence of environment on health throughout the life-course and eventually support more comprehensive assessment of the developmental origins of health and diseases.

Awardees:

• Icahn School of Medicine at Mount Sinai, New York City, New York
• RTI, Research Triangle Park, North Carolina
• University of Minnesota, Minneapolis, Minnesota
• Wadsworth Center, Albany, New York
• Westat, Inc., Rockville, Maryland